Hmm..
Well, I was hoping to stick with the solar system for the early part of the roleplay. Later on we may move on..
As for planets, Venus, Earth, The Moon and Mars are all more or less colonized. There's also the tons of satellite stations and free-floating space-wanderers..
As far as species, there's a ton of variety just with humans. Most of humanity has at least been slightly altered genetically. Most of this is just small things, like some resistance to certain chronic illnesses and such.
There's also the changes made to ease colonization. Like most people living on Luna (The Moon) are gene tweaked so that they don't suffer as much physical degeneration as they normally would due to the low gravity. They're still a bit weaker (And freakishly tall) when compared to people from Earth or Venus.
As for aliens.. You may bump into a few if we start at a trade center type city (Which we may).
I did add a second alien species template to the first post..
“She'd become a governess. It was one of the few jobs a known lady could do. And she'd taken to it well. She'd sworn that if she did indeed ever find herself dancing on rooftops with chimney sweeps she'd beat herself to death with her own umbrella.”
― Hogfather